Question #31802

1 Answer
Nov 15, 2016

Here's how you can do that.

Explanation:

Your first goal here will be to determine how many grams of amoxicillin you need in order to have in your target solution.

A solution's parts per million concentration, ppm, expresses the number of grams of solute present in 10^6 grams of solvent. Simply put, a "1 ppm" solution will have "1 g" of solute in 10^6"g" of solvent.

If you take water's density to be equal to "1.0 g mL"^(-1), you can say that the target solution contains

5 color(red)(cancel(color(black)("mL"))) * "1 g"/(1color(red)(cancel(color(black)("mL")))) = "5 g"

of water. Notice that because your solution contains a very, very small amount o amoxicillin, you can safely assume that the mass of the solution is equal to the mass of the water.

Now, a "20 ppm" amoxicillin solution will contain "20 g" of amoxicillin for every 10^6"g" of water. You can thus say that your sample will contain

5 color(red)(cancel(color(black)("g water"))) * "20 g amoxicillin"/(10^6color(red)(cancel(color(black)("g water")))) = 1 * 10^(-4)"g amoxicillin"

At this point, you should focus on determining the volume of amoxicillin solution that contains 1 * 10^(-4)"g" of solute. Your stock solution is 1%"m/v" amoxicillin, which basically means that it contains "1 g" of solute for every "100 mL" of solution.

You can thus say that you need

1 * 10^(-4) color(red)(cancel(color(black)("g amoxicillin"))) * "100 mL stock"/(1color(red)(cancel(color(black)("g amoxicillin")))) = "0.01 mL stock"

Therefore, you can prepare your solution by taking "0.01 mL" of your "1% m/v" amoxicillin stock solution and adding enough water to get the final volume to "5 mL".

This will get you "5 mL" of "20 ppm" amoxicillin solution.