Assuming that by tan−1(4x) you mean arctan(4x) and not cot(4x).
We know the pythagorean identity sin2(θ)+cos2(θ)=1, so if we divide both sides by #sin^2(theta) we'd have:
sin2(θ)sin2(θ)+cos2(θ)sin2(θ)=1sin2(θ)→
1+cot2(θ)=csc2(θ)
So, if we switch in θ for arctan(4x), we have
1+1tan2(arctan(4x))=1sin2(arctan(4x))
Knowing that tan(arctan(θ))=θ
1+1(4x)2=1sin2(arctan(4x))
Taking the least common multiple so we can sum the two fractions on the right side:
16x2+116x2=1sin2(arctan(4x))
Invert both sides
16x216x2+1=sin2(arctan(4x))
Taking the square root
√16x216x2+1=sin(arctan(4x))
Simplifying
4x√16x2+1=sin(arctan(4x))
You can rationalize it if you want
4x⋅√16x2+116x2+1=sin(arctan(4x))
And last but not least, gotta list out the values x can't be because of the liberities we took during our process. We can't have denominators being zero nor negatives in square roots, so we have:
(4x)2≠0
16x2+1>0
sin(arctan(4x))≠0→4x√16x2+1≠0
From these we see that x≠0