Question

Does alcohol promote inflammation in the body?

Answer 1

Depends on the intake pattern...

Explanation:

Alcohol taken in moderation has a positive effect: it lowers the risk of cardiovascular problems.

Excessive intake and chronic alcoholism however, DO affect the immune system in a negative way.

Amongst other problems, the Gastro-intestinal flora produce a class of (bio-)molecules called LipoPolySaccharides. (Glycosylated lipids). These have a negative effect on our body, but are kept under control by various organs, most prominently the liver. Also, the CNS contributes to this via the NeuroImmune system.

Chronic alcohol (ab)use impairs not only gastro-intestinal and liver functions, but also multi-organ interactions, leading to persistent systemic inflammation and ultimately, to organ damage...