Viral Replication
Key Questions
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Viruses (virions) have to make more copies of themselves so they can spread. This is what we call viral replication.
In general, virus replication goes through the following five steps:
1. Adsorption, the attachment of viruses to host cells.-
Penetration, the entry of virions (or their genome) into host cells. Some leave the capsid and envelope behind.
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Synthesis, the synthesis of new nucleic acid molecules, capsid proteins, and other viral components within host cells while using the metabolic machinery of those cells. They hijack the cells' metabolic processes.
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Maturation, the assembly of newly synthesized viral components into complete virions.
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Release, the departure of new virions from host cells. Release generally, but not always, kills (lyses) host cells. (Some types will wait for a long time while hiding and are said to be lysogenic).
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